PIT21 EXPLORING COST OF AND TREATMENT PATTERNS WITH AUTOGRAFT DURING HOSPITALIZATIONS FOR THERMAL BURN PATIENTS IN A COMMERCIALLY INSURED POPULATION

Abstract

This study assessed the treatment patterns, healthcare resource utilization (HCRU), and cost of care during hospitalizations for thermal burn patients who were treated with autograft, which is included in the current standard of care for severe burns. The Truven Health MarketScan® Database was used to identify thermal burn patients who were treated with a first inpatient autograft between 01/01/2011 and 06/30/2016. The first admission was noted as the index hospitalization. Forty-five-day pre- and 6-month post-index continuous enrollment were required. Patient demographics, clinical characteristics, treatment patterns, HCRU, and total cost were reported. Of 1,695 patients included in this analysis, mean age was 36.6 years (SD=18.5), 1,124 (66.3%) were males, 1,566 (92.4%) had third degree or deep third degree burns, and 572 (33.7%) had ≥10% total burn surface area (TBSA). The majority of burn sites were in upper or lower limbs (66.3% and 56.2%, respectively). During the index hospitalizations, mean overall length of stay (LOS) was 14.2 days (SD=18.8) (Mean LOS: 7.8 days for <10% TBSA, 13.1 days for 10%–19% TBSA, 21.1 days for 20%–29% TBSA, and 42.8 days for ≥30% TBSA); mean total cost was $133,613 (SD=$260,552); 238 (14.0%) patients had nonautologous/homograft/heterograft procedures; 526 (31.0%) patients had synthetic substitute procedures; 6 (0.4%) patients had pedicle grafts or flaps procedures. 1,623 (95.8%) patients received debridement; 131 (7.7%) patients were treated with respiratory intubation and mechanical ventilation. 1,178 (69.5%) and 1,122 (66.2%) patients received physical therapy and occupational therapy, respectively. Approximately 64% of patients were admitted through ER. During 45-day pre-index, 562 (33.2%) patients had burn-related outpatient ER visit; 236 (13.9%) patients had burn-related hospitalization. 110 (6.5%) patients had all-cause 30-day readmission. Among them, 67.3% were burn-related. The economic burden of hospitalizations for thermal burn patients who were treated with autograft was substantial. Treatment included various graft materials along with autograft during hospitalizations.