Pit pattern classification for diagnosis of early colorectal cancers and precancerous lesions

Abstract

Objective To evaluate pit pattern analysis for detection of early colorectal carcinoma and precancerous lesions. Methods A total of 162 lesions in 144 patients were examined with magnifying colonoscopy after staining, and their pit patter was analyzed with morphology and pathologic diagnosis. Results With confirmation of pathology, there were 34 non-neoplastic lesions and 128 neoplastic ones, in which 12 were carcinomas. The pit patterns in most non-neoplastic lesions （76. 5%, 26/34） were type Ⅰ or Ⅱ , and those in most neoplastic lesions （96. 1% , 123/128） was type Ⅲ, Ⅳ or Ⅴ. Pit patterns of cancerous lesions were mainly type Ⅴ （75.0%, 9/12）, and those of 3 cases of advanced cancers were all type Ⅴ N. Conclusion Pit pattern classification is a very important tool to differentiate between neoplastic, nonneoplastic lesions and early cancer, which helps to decide later therapeutic intervention. Key words: Endoscopy,digestive system; Intestinal neoplasms; Pit pattern; Staining