Pineal Tumors (PPTID, PTPR)

Abstract

Pineal parenchymal tumors are categorized into WHO Grade I pineocytoma, WHO Grade II or III pineal parenchyma tumor of intermediate differentiation (PPTID), and WHO Grade IV pineoblastoma. Aggressive surgery to achieve gross total resection (GTR) may be challenging in the pineal region due to the risk of neurologic injury. There is currently no consensus from phase III prospective data to guide adjuvant therapy in PPTID, but focal radiotherapy should be considered in this setting to improve local control. Papillary tumors of the pineal region (PTPR) is another rare neuroectodermal tumor with limited published literature and no established guidelines with respect to adjuvant therapy after surgical resection; however, focal radiotherapy should also be considered to improve local control. In this chapter, we present general principles of treatment planning for these two disease entities of the pineal region.KeywordsPineal parenchyma tumor of intermediate differentiation (PPTID)Papillary tumors of the pineal region (PTPR)