Pindborg Tumor-An Uncommon Odontogenic Tumor Detected by 68Ga-DOTATOC.

Anna Herden,Christian Furth,Christian Doll,Katja Warnecke,Deema Sabtan

doi:10.3390/diagnostics12020389

Abstract

A 62-year-old-woman with a suspected Tumor-induced-osteomalacia (TIO), a rare neoplastic syndrome that results in renal phosphate wasting with hypophosphatemia, underwent 68Ga-DOTATOC PET/CT on the suspicion of a mesenchymal tumor producing Fibroblast growth factor 23 (FGF23). Imaging revealed a small osteolytic, somatostatin receptor (SSTR) positive lesion containing calcifications in the alveolar process of the maxilla. No other SSTR-positive focus was found. A biopsy was performed by an oral and maxillofacial surgeon that revealed a calcifying epithelial odontogenic tumor (Pindborg tumor). This case shows that epithelial odontogenic tumors as an uncommon benign tumor entity can also be SSTR-positive.

Highlights

A 62-year-old-woman with a suspected Tumor-induced-osteomalacia (TIO), a rare neoplastic syndrome that results in renal phosphate wasting with hypophosphatemia, underwent 68GaDOTATOC PET/CT on the suspicion of a mesenchymal tumor producing Fibroblast growth factor 23 (FGF23)
A biopsy was performed by an oral and maxillofacial surgeon that revealed a calcifying epithelial odontogenic tumor (Pindborg tumor). This case shows that epithelial odontogenic tumors as an uncommon benign tumor entity can be somatostatin receptor (SSTR)-positive
A 62-year-old woman with suspected Tumor-induced-osteomalacia (TIO) because of biochemical evidence of Fibroblast growth factor 23 (FGF23) after several fractures caused by low bone density underwent somatostatin receptor imaging PET/CT (SSTR-PET/CT) using 68Ga-DotaTOC

Summary

Introduction

A 62-year-old woman with suspected Tumor-induced-osteomalacia (TIO) because of biochemical evidence of Fibroblast growth factor 23 (FGF23) after several fractures caused by low bone density underwent somatostatin receptor imaging PET/CT (SSTR-PET/CT) using 68Ga-DotaTOC. Abstract: A 62-year-old-woman with a suspected Tumor-induced-osteomalacia (TIO), a rare neoplastic syndrome that results in renal phosphate wasting with hypophosphatemia, underwent 68GaDOTATOC PET/CT on the suspicion of a mesenchymal tumor producing Fibroblast growth factor 23 (FGF23). Imaging revealed a small osteolytic, somatostatin receptor (SSTR) positive lesion containing calcifications in the alveolar process of the maxilla.

Results

Conclusion