Abstract
Influenza is associated with considerable morbidity and mortality and remains important for public-health surveillance and prevention efforts. Every year about 5-10% of adults and up to 15% of children develop influenza; more than 700,000 cases in Austria. The virus causes significant follow-up costs. The vaccine is recommended for all persons >6 months, elderly, chronically ill, people at-risk and healthcare-professionals. The aim of the BIA is to quantify the monetary-impact due to the current situation of influenza vaccination, expressed as world with vaccination, compared to a world without vaccination. A multi-cohort, population-based model (age and risk-groups) was developed over a 5-year time-horizon, which included the following states: hospitalized and outpatient influenza, complications (bronchitis, pneumonia, URTI, CV, CNS, renal, otitis-media, GI-bleeding) and mortality. In the world with vaccination individuals received vaccination (9.2% 1st year to 14.4% 5th year) or no vaccination according the current market-share. The model includes probabilities for virus A and B. Results showed which savings could be achieved from the health-care-systems perspective and from the societal perspective. Vaccination costs are based on the present pharmacy-selling-price, which is payed out-of-pocket. Based on the current vaccination coverage annual savings of 40.9 million € (m€) (1st year) to 65.6 m€ (5th year) [total: 274.6 m€ over 5 years] could be achieved. Direct costs contributed between 3.3 m€ (1st year) to 7.3 m€ (5th year) [total: 28.3 m€] to total saving. The society is relieved due to a vaccination strategy. The savings in indirect costs range from 37.5 m€ (1st year) to 58.4 m€ (5th year) [total: 246.3 m€]. The costs of the vaccination are borne by the patients, who make private payments of 1.6 m€ (1st year) to 2.4 m€ (5th year) [total: 10.1 m€]. 1€ private invested in the influenza vaccine relieves the society with 27.23€ and saves 2.81€ in health-care-system.
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