Abstract
Adhesion of cells to biotic and abiotic surfaces is a key for the exchange of genetic material, multicellular development, and colonization of the environment. In fungi, these functions are mediated by fungal adhesins, a family of secreted cell wall glycoproteins that recognize specific carbohydrate or peptide ligands. High-resolution 3D structures of adhesins from apathogenic and pathogenic yeasts now reveal how these proteins confer social interactions and fungal pathogenesis.
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