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Abstract
A pilot-scale continuous Chromatograph has been developed for optimization studies and scaling factor evaluations. The continuous annular Chromatograph consists of a slowly rotating annular bed of ion exchange resin to which feed is continuously introduced at a stationary point at the top of the bed while eluent flows over the remainder of the annulus. The rotation of the sorbent bed coupled with the simultaneous elution chromatography causes the separated components of the feed stream to appear as helical bands, each of which has a characteristic, stationary exit point.
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