Abstract
Currently, 7.6% of the U.S. young adults aged 18–24 years old use e-cigarettes. This study piloted three methods of Electronic Nicotine Delivery Systems (ENDS) cessation by measuring cessation rates, motivational techniques that contributed to cessation success, and participants’ changes after decreasing vape use. Participants were randomized into three study arms (nicotine replacement therapy (NRT) + behavioral support, vape-taper + behavioral support, self-guided) in a 1:1:1 ratio. All participants were invited to attend nine in-person or phone appointments over the 6-month study period. At 12 weeks, 3 of 7 (42.9%) participants in the NRT + behavioral support arm, 6 of 8 (75%) vape-taper + behavioral support arm, and 7 of 9 (77.8%) self-guided arm self-reported being vape-free and nicotine-free. At 6 months, 3 of 7 (42.9%) participants in the NRT + behavioral support arm, 6 of 8 (75%) vape-taper + behavioral support arm, and 4 of 9 (44.4%) self-guided arm self-reported being vape-free and nicotine-free. A challenge to quitting and remain quit is social pressures, but participants identified self-control and establishing new habits to be the best methods to overcome the desire to vape. Participants who received behavioral support and a vape-taper plan from pharmacists were more likely to be vape-free and nicotine-free at 6 months.
Highlights
Electronic nicotine delivery systems (ENDS), commonly referred to as vapes or ecigarettes, have gained popularity in recent years, especially among teens and young adults [1]
While many people believe Electronic Nicotine Delivery Systems (ENDS) to be safer than combustible cigarettes, research has shown that ENDS users obtain plasma nicotine concentrations similar to combustible products and have been linked to many health issues [8,9,10,11,12,13]
Twenty-nine individuals set up initial appointments, but initial data was only collected for 24 participants due to failure to attend the initial appointment (Supplemental Figure S1)
Summary
Electronic nicotine delivery systems (ENDS), commonly referred to as vapes or ecigarettes, have gained popularity in recent years, especially among teens and young adults [1]. The most recent U.S data reports 7.6% of 18–24-year-olds use electronic cigarettes and 1.7% of 18–24-year-olds are dual users of combustible cigarettes and electronic cigarettes [2]. 30.7% of ENDS users reported recent use of at least one combustible tobacco product at a six-month follow-up, compared to 8.1% of participants who had never used ENDS [7]. While many people believe ENDS to be safer than combustible cigarettes, research has shown that ENDS users obtain plasma nicotine concentrations similar to combustible products and have been linked to many health issues [8,9,10,11,12,13]. Since 2019, e-cigarette or vaping product use associated lung injury (EVALI) has been diagnosed in over 2800 patients and the cause of 68 deaths [9]
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