Abstract
A prospective study was conducted in patients with early-stage gastric cancer to determine the efficacy and safety of acupuncture stimulation as an antispasmodic compared with conventional medication during the procedure of endoscopic submucosal dissection (ESD) of the upper gastrointestinal tract. This study was a prospective single blinded quasi-randomized controlled trial. Seventy-three patients who were scheduled to undergo ESD for gastric cancer at Aizu Medical Center between 19 February 2016 and 30 June 2016 were assessed for eligibility for the study. Sixty out of 73 patients were included in the study and assigned into two intervention groups: medication group (MG) and acupuncture group (AG). Ease of the procedure was evaluated using modified NIWA classification (MNC) by endoscopist considering the frequency and amplitude of the upper gastrointestinal peristalsis. For the statistical analysis, Mann–Whitney test was used to compare the differences of MNC values (baseline and end of procedure) between two groups. The difference of MNC found in the AG (−2.00 (−3.0 to −2.0)) was significantly greater than that in the MG (−1.00 (−2.0 to −1.0), p < 0.0001, Mann–Whitney test). We consider that acupuncture to the abdomen could be an alternative antispasmodic method during upper gastrointestinal endoscopic procedure.
Highlights
IntroductionAdverse events during endoscopic submucosal dissection (ESD) procedure such as perforation and bleeding may be caused by poor visualization of the resection area besides fibrosis or scars [3,4,5]
Endoscopic submucosal dissection (ESD) is a procedure that enables en bloc resection of gastric neoplastic lesions, and endoscopic submucosal dissection (ESD) is the first-line treatment for early-stage gastrointestinal cancer [1,2]. 4.0/).Adverse events during ESD procedure such as perforation and bleeding may be caused by poor visualization of the resection area besides fibrosis or scars [3,4,5]
We found that acupuncture stimulation on the abdomen, by its gastric relaxation effect, suppressed the gastric peristalsis and made the procedure easier than with the antispasmodic agent
Summary
Adverse events during ESD procedure such as perforation and bleeding may be caused by poor visualization of the resection area besides fibrosis or scars [3,4,5]. As the gastric peristalsis especially hinders the field of vision and makes the procedure difficult, it is important to inhibit gastric peristalsis from the early phase of the ESD procedure. Antispasmodic agents such as “anticholinergics” and “glucagon” are used, but for patients with underlying diseases such drugs may be contraindicated or require careful administration. As the number of patients with lifestyle-related diseases increases, we may see more situations in which such antispasmodic drugs are not preferable in gastrointestinal procedure. There is an increased desire to develop an alternative method to antispasmodic agents
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
