Pilot programme - detection of colon tumour in subjects living in the district of northern Banat

Abstract

Tumours of the colon are among the leading neoplasms in the world as well as in Europe and our country both in the male and female population. The study was aimed at showing the incidence of colon tumour in a group of 300 subjects who had undergone total colonoscopy as well. The endoscopic examinations were performed by the Fujinon video endoscopes. The faecal occult blood test was done by the original test 'ULTI Med Products Deutschland GmbH' The biopsy specimens were delivered to the Pathomorphological Service to be processed andstained by the method of Hematoksilin-eosin. A group of 300 subjects, consisting of 144 men (48%) and 156 women (52%) were examined. The indication for the lower endoscopy in 52 patients (17.33%) was manifest bleeding The faecal occult blood test was positive in 79 patients (26.33). The endoscopic examination verified 25 colon polyps (8.33%) and 14 malignant colon tumours (4.60%) in the examined group. The endoscopy was also performed in 48 patients who had been already operated for colon carcinoma (16%) and in 5 patients who had undergone endoscopic polypectomy (1.66%). Specificity, sensitivity and predictivity were calculated to be 55.8%, 63% and for positive finding 9.4% and for negative finding 95.8%, respectively, for the Haemoccult test as compared to the histological finding as a "gold standard" The obtained results were compared with the findings of other authors. Our opinion, formed according to the obtained results and findings of other authors, is that it is necessary to perform systematic examination of people over 45 years of age for early detection of colon tumour.