Abstract
Background Right ventricular (RV) T1 quantification is desirable in managing congenital heart disease and pulmonary hypertension patients where RV fibrosis is implicated. RV T1 quantification is technically difficult because of the thin trabeculated mobile wall of complex geometry, impacted by adjacent blood and epicardial fat, plus proximity to sternal wires in some cases. Prior work has measured RV T1 by multi-shot segmented imaging, further by IDEAL fat-water separation in SASHA extended to suppress blood signal by inflow of saturated blood. We present initial results by single-shot imaging with motion-corrected (MoCo) averaging aiming to: 1) reduce ghost artifacts arising in a segmented scan, 2) apply fat-water separation, 3) null blood within the RV, 4) facilitate anchor image acquisition and 5) permit free-breathing acquisition.
Highlights
Right ventricular (RV) T1 quantification is desirable in managing congenital heart disease and pulmonary hypertension patients where RV fibrosis is implicated
The MSPrep aimed to null blood signal by through-slice velocity-sensitized dephasing without losing myocardial signal, by adjustable time of application and velocitysensitivity Field-of-Speed[4]
Mean RV free wall and septal T1s were independently measured by two observers from 2-parameter fit pixelwise maps assuming h=1
Summary
Right ventricular (RV) T1 quantification is desirable in managing congenital heart disease and pulmonary hypertension patients where RV fibrosis is implicated. We present initial results by single-shot imaging with motion-corrected (MoCo) averaging aiming to: 1) reduce ghost artifacts arising in a segmented scan, 2) apply fat-water separation, 3) null blood within the RV, 4) facilitate anchor image acquisition and 5) permit free-breathing acquisition
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