Abstract
We have conducted a pilot clinical study to not only investigate the sub-THz spectra of ex-vivo fresh human whole blood of 28 patients following 8-hours fasting guideline, but also to find out the critical blood ingredients of which the concentration dominantly affects those sub-THz spectra. A great difference between the sub-THz absorption properties of human blood among different people was observed, while the difference can be up to ~15% of the averaged absorption coefficient of the 28 samples. Our pilot clinical study indicates that triglycerides and the number of red blood cells were two dominant factors to have significant negative correlation to the sub-THz absorption coefficients.
Highlights
23. ATP III At-A-GlanceSkorobogatiy, “High-refractive-index composite materials for terahertz waveguides: trade-off between index contrast and absorption loss,” JOSA B 28(4), 917-921, (2011)
Blood is the most important body fluid, containing many kinds of proteins, lactose, blood cells, and salts
Even though it is reasonable to understand the observation on the negative correlation between TG concentration and THz absorption due to that lipids absorb much less THz power than water, it is harder to understand the comparatively high p-value for the analysis on total cholesterol (T-CHO), due to the fact that both T-CHO and TG are with a similar mass concentration per unit volume of blood
Summary
Skorobogatiy, “High-refractive-index composite materials for terahertz waveguides: trade-off between index contrast and absorption loss,” JOSA B 28(4), 917-921, (2011). “Electromagnetic Material” in Plasmonics: Fundamentals and applications, Springer, (2007). Grischkowsky, "Terahertz time-domain spectroscopy of water vapor," Opt. 27. B. Madsen, "Analysis of Qualitative Data" in Statistics for non-statisticians, Springer, 2008. B. Madsen, "Assessment of Relationship" in Statistics for non-statisticians, Springer, 2008. M. Cox, "Lipid Biosynthesis" in Principle of Biochemistry, W.
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