Abstract
A clinicopathologic analysis of 92 pilomatrixomas in 84 children was made. The diagnosis is seldom made clinically, since the lesions are not distinct and are referred to most often as some variety of cyst. The common locations are the face, neck, and arms. The lesion is benign and is cured by excision. In our patients the diagnosis was always established by pathologic study. There are similarities between pilomatrixoma and pilar structures. The tumor probably originates from a primitive cell of the primary epithelial germ and differentiates toward hair-matrix cells. The name "pilomatrixoma" is acceptable, since it conveys the histogenesis of the lesion and avoids the word "epithelioma," which generally indicates a malignant neoplasm and should not be used for this benign tumor.
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