Abstract

Pilomatrix Carcinoma (PC) is an exceedingly rare neoplasm. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. Although early recognition and treatment is paramount in optimization of outcomes for this aggressive carcinoma, the diagnosis is complicated by shared features with its more common benign counterpart. In patients with recurrence or rapid growth of a pilomatrixoma, pilomatrix carcinoma should be considered in the differential diagnosis.

Highlights

  • Pilomatrixoma is a slow growing dermo-hypodermic tumor arising from hair matrix cells [1]

  • Early recognition and treatment is paramount in optimization of outcomes for this aggressive carcinoma, the diagnosis is complicated by shared features with its more common benign counterpart

  • In patients with recurrence or rapid growth of a pilomatrixoma, pilomatrix carcinoma should be considered in the differential diagnosis

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Summary

Introduction

Pilomatrixoma is a slow growing dermo-hypodermic tumor arising from hair matrix cells [1]. Pilomatrix Carcinoma (PC) is a very rare neoplasm, with approximately 90 total cases reported to date, and fewer than 25 cases reported in the face and scalp [2,3]. Predilection for sites is the same for the benign and malignant variants [1]. We report the only case that presented at our tertiary care center over the past 30 years and provide an up to date review of the literature

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