PIH24 Economic Evaluation of Ulipristal Acetate Tablets for the Treatment of Patients with Moderate and Severe Symptoms of Uterine Fibroids

Abstract

The cost effectiveness analysis compares ulipristal acetate to (1) pre-surgical observation and (2) immediate hysterectomy. A Markov state-transition economic model was developed over a 10 year time horizon. The model comprises mutually exclusive health states: no/mild bleeding disorder, heavy bleeding disorder, persistent heavy bleeding disorder, myomectomy, post-myomectomy with no/mild bleeding disorder, post-myomectomy with heavy bleeding disorder, hysterectomy, posthysterectomy, post-menopausa and death.