Pig farm vaccination against classical swine fever reduces the risk of transmission from wild boar

Abstract

In 2018, classical swine fever (CSF) re-emerged in the Gifu Prefecture, central Japan, causing an on-going outbreak among wild boars and domestic pigs in the country. Consequently, oral vaccination for wild boar and compulsory vaccination for pig farms started in 2019. We have previously shown that, before vaccination in the Gifu Prefecture, the presence of CSF-infected wild boar near pig farms increased the risk of CSF transmission. This study aimed to re-evaluate the transmission risk from wild boars to pig farms under a vaccination program. The effectiveness of vaccination was evaluated by comparing the transmission risk estimated before and after the implementation of vaccinations.In this study, we focused on two affected areas, the Kanto (eastern Japan) and Kinki (west-central Japan) regions, in which eight of 11 infected farms were detected between the start of pig farm vaccinations and April 2021. Wild boar surveillance data from an area within a 50-km radius from the infected farms were used for analysis, consisting of 18,870 1-km grid cells (207 infected cells) in the Kanto region, and 15,677 cells (417 infected cells) in the Kinki region.The transmission rates in the post-vaccination period in the Kanto and Kinki regions were much lower than that in the pre-vaccination period in the Gifu Prefecture. The values of transmission kernels (h0, transmission rate at 0 km) in the Kanto and Kinki regions decreased to 1% of the transmission kernel in the pre-vaccination period. In the pre-vaccination period, the risk of infection within 300 days was almost 95 % when one infected grid cell was detected within 1 km of a pig farm. Meanwhile, in the post-vaccination period, the risk of infection within 300 days was approximately 5% when several infected cells were detected within 1 km of a pig farm.Considering the limited effect of oral vaccination for wild boar due to distribution limitations in the Kanto and Kinki regions, vaccination on pig farms may seems to have mainly reduced the transmission risk from wild boar. However, despite the implementation of vaccination, the risk of infection on pig farms remains present due to the immunity gap of weaning pigs. Therefore, strict biosecurity measures on pig farms and an appropriate vaccination program are required to prevent and control CSF spread.