Abstract
Piezoelectric substrates enable the generation of mechanical forces with Angstrom resolution via an applied voltage. When using such a substrate for planar patch clamp experiments, these deformations will induce tension in the lipid membrane. This will, in turn, affect the conductive properties of any mechanosensitive ion channels in the membrane, as well as mechanically perturb any other proteins embedded in the cell membrane. We show that an applied electric field induces structural changes in our piezoelectric quartz substrates and, thus, to the micron-sized pores in the quartz.
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