Abstract

In the past few decades, probabilistic interpretations of brain functions have become widespread in cognitive science and neuroscience. In particular, the free energy principle and active inference are increasingly popular theories of cognitive functions that claim to offer a unified understanding of life and cognition within a general mathematical framework derived from information and control theory, and statistical mechanics. However, we argue that if the active inference proposal is to be taken as a general process theory for biological systems, it is necessary to understand how it relates to existing control theoretical approaches routinely used to study and explain biological systems. For example, recently, PID (Proportional-Integral-Derivative) control has been shown to be implemented in simple molecular systems and is becoming a popular mechanistic explanation of behaviours such as chemotaxis in bacteria and amoebae, and robust adaptation in biochemical networks. In this work, we will show how PID controllers can fit a more general theory of life and cognition under the principle of (variational) free energy minimisation when using approximate linear generative models of the world. This more general interpretation also provides a new perspective on traditional problems of PID controllers such as parameter tuning as well as the need to balance performances and robustness conditions of a controller. Specifically, we then show how these problems can be understood in terms of the optimisation of the precisions (inverse variances) modulating different prediction errors in the free energy functional.

Highlights

  • Probabilistic approaches to the study of living systems and cognition are becoming increasingly popular in the natural sciences

  • PID controllers are renowned for their simplicity and straightforward interpretation in control theory, a general interpretation in probabilistic frameworks (e.g., Bayesian inference) is still missing

  • While methods such as PID control are still widely adopted as models of biological systems, it is unclear how general theories such as active inference connect to practical implementation of homeostatic principles such as PID control

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Summary

Introduction

Probabilistic approaches to the study of living systems and cognition are becoming increasingly popular in the natural sciences. In particular for the brain sciences, the Bayesian brain hypothesis, predictive coding, the free energy principle and active inference have been proposed to explain brain processes including perception, action and higher order cognitive functions [1,2,3,4,5,6,7,8]. According to these theories, brains, and biological systems more generally, should be thought of as Bayesian inference machines, since they appear to estimate the latent states of their sensory input in a process consistent with a Bayesian inference scheme. While initially the theory emerged in the computational [12]

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