Abstract

Nine new drimane-type sesquiterpenoids: 3α-acetoxypolygodial, 3α-acetoxypolygodial 12-dimethyl acetal, 9-deoxymuzigadial 12α-acetal, 9-deoxymuzigadial 12β-acetal, 3β-acetoxypolygodial 12α-acetal, 3β-acetoxypolygodial 12β-acetal, 9-epideoxymuzigadial, 3β-acetoxypolygonal and muzigaal, were isolated from the leaves of Canella winterana, together with six previously known sesquiterpenoids; muzigadial, 3β-acetoxypolygodial, 3β-acetoxycinnamolide, isopolygodial, polygodial 12α-acetal and drimenol. Unambiguous assignments of all 1H and 13C signals of 15 sesquiterpenoids were established by 2D NMR experiments.

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