PHYTOPHARMACOLOGICAL REVIEW OF KNEMA ATTENUATA (HOOK F. AND THOMSON) WARB

Supriya Raja H,Sreekanth G B

doi:10.22159/ijcpr.2021v13i3.42089

Abstract

Knema attenuata, a member of Myristicaceae family and commonly known to world as ‘wild nutmeg’ is broadly used in folk medicine for treating ailments such as jaundice, chronic fever, inflammations, spleen disorders, breathing disorders and impaired taste sensation. This review article aims to compile all the updated information on the phytochemical and pharmacological activities of plant Knema attenuata. Studies indicate that different parts such as aril, seed and stem bark of the plant is rich in phenolics, flavonoids, tannins, steroids, terpenes, resins and glycolipids. Moreover, stem bark of Knema attenuata contains a lignan ‘attenuol’ with diverse pharmacological activities. In addition, different extracts of plant parts have been found to possess various pharmacological activities such as antioxidant, antifungal, larvicidal, analgesic, anti-inflammatory, antihyperlipidemic, and hepatoprotective activities. More research on phytochemical composition and therapeutic implications are recommended.

Highlights

Plants have always played a remarkable role in human health care since ancient times
Knema is a genus belonging to Myristicaceae family, distributed in tropics and subtropics of Indomalesia region which includes around 93 species widely used in folk medicine [3]
This review article demonstrates the traditional importance of the plant Knema attenuata

Summary

Introduction

Plants have always played a remarkable role in human health care since ancient times. Potions, and powders have been used, for centuries, by traditional herbal healers for curing ailments. A large number of plant extracts have been screened to isolate and purify the bioactive components which can be potential drug leads. Knema is a genus belonging to Myristicaceae family, distributed in tropics and subtropics of Indomalesia region which includes around 93 species widely used in folk medicine [3]. This genus mostly consists of smallmedium trees has been used to treat sores, pimples, rheumatism, and cancer.

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Conclusion