Abstract

In recent years, a plethora of extraction processes have been performed by a novel class of green solvents known as deep eutectic solvents (DESs), possessing several environmental, operational, and economic advantages proven by experience when compared to organic solvents and ionic liquids. The present review provides an organized overview of the use of DESs as extraction agents for the recovery of valuable substances and compounds from the original plant biomass, waste from its processing, and waste from the production and consumption of plant-based food. For the sake of simplicity and speed of orientation, the data are, as far as possible, arranged in a table in alphabetical order of the extracted substances. However, in some cases, the isolation of several substances is described in one paper and they are, therefore, listed together. The table further contains a description of the extracted phytomass, DES composition, extraction conditions, and literature sources. With regard to extracted value-added substances, this review addresses their pharmacological, therapeutic, and nutritional aspects. The review also includes an evaluation of the possibilities and limitations of using DESs to obtain value-added substances from phytomass.

Highlights

  • Biomass is considered to be any organic material produced by the growth of microorganisms, plants, or animals, involving wastes and residues of organic nature [1,2]

  • Primary biomass and biowaste generated during its treatment, processing, and use are the source of a huge number of compounds and substances, referred to as value-added products, which can be extracted, recovered, and/or synthesized from biomass [3]

  • The extraction of value-added compounds is often associated with the pretreatment of phytomass, which means the treatment of the inputted raw phytomass, e.g., by mechanical milling prior to the action of deep eutectic solvents (DESs) as extractants to facilitate the penetration of DES

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Summary

Introduction

Biomass is considered to be any organic material produced by the growth of microorganisms, plants, or animals, involving wastes and residues of organic nature [1,2]. Biomass is a renewable energy source, the second oldest source of energy following the Sun. Primary biomass and biowaste generated during its treatment, processing, and use are the source of a huge number of compounds and substances, referred to as value-added products, which can be extracted, recovered, and/or synthesized from biomass [3]. The ways of obtaining such value-added products are covered under the term valorization. The main mode of obtaining value-added products from phytomass and discussed in this review are extraction processes. This work is aimed at providing an overview of the obtained value-added products, their phytomass sources, used DESs, and conditions of valorization. Crystals 2020, 10, 800 achieved in the last few years and indicates the perspectives, and the limitations of the development of this area

Deep Eutectic Solvents
Requirements for Extracting Agents
Thermal Stability
Temperature Range of Liquid State
Viscosity
Polarity
Acid-Base Properties
Therapeutic Effects of Substances Extracted from Phytomass
Valorization of Phytomass by Deep Eutectic Solvents
Extracted Value-Added Compounds
Total Polyphenols
Phlorotannins
Flavonoids
Catechins
Curcumin
Caffeoylquinic Acids
Isoflavones
Hesperidin
7.10. Terpenes
7.11. Ginkgolides
7.12. Glycyrrhetinic Acid
7.13. Artemisinin
7.14. Polyprenol Acetates
7.15. Proteins
Purity
Hygroscopicity
Long-Term Stability
Toxicity
Adsorbable Organic Halides
Recycling
Findings
Future Trends and Concluding Remarks

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