Abstract

The genus Ziziphus (Rhamnaceae) species are examples of multipurpose plants with great potential for ethnomedicinal use. The analysis and extraction of plant material play an important role in the development, modernization and quality control of herbal formulations. Gas chromatography and Mass spectroscopy (GC-MS) techniques have become a sophisticated means for analysis of various compounds . The phytoconstituents from n-hexane and 70% ethanol leaves extracts of Ziziphus nummularia (Burm. f.) Wight & Arn. family Rhamnaceae was studied. The GC-MS analysis revealed the presence of total 105 and 56 phytoconstituents in n-hexane and 70% ethanol extract, respectively. Some of these compounds which were present in major amount were palmitic acid, linoleic acid, stearic acid, squalene, stigmasterol, campesterol, vitamin E, geranyl linalool isomer, trans-geranylgeran oil, 1-eicosanol, gamma sitosterol, betulin, lupeol and phytol in n-hexane extract while beside palmitic acid, linoleic acid, gamma sitosterol, stigmasterol, phytol, and squalene, oleic acid, tricosane, tetradecane, 2 methoxy-4-vinylphenol, ethyl alpha-d-glucopyranoside, and behenyl behenate were present in 70% ethanol extract of Ziziphus nummularia leaves. Many of the compounds present in both the extracts are used for medicinal purposes such as squalene consists of antioxidant, anti-inflammatory, antitumor activity; phytol have antimicrobial activities, anti-tumorous, anti-teratogenicity, anti-inflammatory, antispasmodic activity; stigmasterol have anti-stiffness and anti-hypercholestrolemic activity. From best of our knowledge this is the first time published study on Ziziphus nummularia (Burm. f.) Wight & Arn. leaves in n-hexane and 70% ethanol extract using GC-MS spectroscopy. Keywords : Ziziphus nummularia, rhamnaceae, phytoconstituents, Gas chromatography and Mass spectroscopy (GC-MS spectroscopy) Cite this Article Sonia, Singh S, Singh SK. Phytoconstituents of Ziziphus nummularia (Burm. f.) Wight & Arn. Leaves Extracts Using GC-MS Spectroscopy. Research & Reviews: A Journal of Life Sciences . 2019; 9(1): 109–118p.

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