Abstract
AbstractAntidenge activity of the n‐hexane, ethyl acetate and n‐butanol extracts from the leaves of Carica papaya against four dengue virus serotypes (DENV1‐4) were evaluated. As a result, the n‐hexane extract showed the best antiviral activity on all denge virus with PNRT50 from 15.625 to 31.25 μg/ml. From n‐hexane extract, nine compounds including cycloartenol (1), cycloart‐23,25‐dien‐3β‐ol (2), cycloart‐25‐ene‐3β,24β‐diol (3), cycloart‐25‐ene‐3β,24α‐diol (4), 25‐hydroxycycloart‐23‐ene‐3‐one (5), β‐sitosterol (6), stigmasterol (7), nonacosan‐1‐ol (8), all‐trans‐polyprenol‐12 (9) were isolated. Structural elucidation of the above compounds was supported by analysis of their spectral data. Compounds 2‐5, 8 and 9 were isolated for the first time from the plant Carica papaya.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
