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Abstract
Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.
Highlights
Plants are potential sources of medicinal compounds and have been used as ancient healing systems since antiquity
One of the most important medicinal plants of genus Withania is Withania coagulans in the Ayurvedic medicinal system owing to its effective nutraceutical as well as pharmaceutical attributes
The berries of the W. coagulans are composed of milk coagulating enzymes, two esterase, free amino acids, and essential oil
Summary
Plants are potential sources of medicinal compounds and have been used as ancient healing systems since antiquity. One of the most important medicinal plants of genus Withania is Withania coagulans in the Ayurvedic medicinal system owing to its effective nutraceutical as well as pharmaceutical attributes. It is grown in various regions of the world such as in the Mediterranean region and from North Africa to South Asia [1]. Among twenty-three identified species of genus Withania, only two (W. coagulans and W. somnifera) have economic significance [2] This plant is widely used to coagulate milk due to the presence of an enzyme in its berries, which is commonly known as an Indian cheesemaker [3]. By considering the growing utilization of medicinal plants and their application in various indigenous health systems, this review is intended to provide comprehensive knowledge on phytochemistry, food uses, and the therapeutic potential of W. coagulans
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