Abstract
Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed across many tropical and subtropical regions. Polyalthia species have been used long term as indigenous medicine to treat certain diseases, including fever, diabetes, infection, digestive disease, etc. Recent studies have demonstrated that not only crude extracts but also the isolated pure compounds exhibit various pharmacological activities, such as anti-oxidant, anti-microbial, anti-tumor, anti-cancer, etc. It is known that the initiation of cancer usually takes several years and is related to unhealthy lifestyle, as well as dietary and environmental factors, such as stress, toxins and smoking. In fact, natural or synthetic substances have been used as cancer chemoprevention to delay, impede, or even stop cancer growing. This review is an attempt to collect current available phytochemicals from Polyalthia species, which exhibit anti-cancer potentials for chemoprevention purposes, providing directions for further research on the interesting agents and possible clinical applications.
Highlights
Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Department of Medical Research, China Medical University Hospital, China Medical University, Abstract: Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed across many tropical and subtropical regions
It is accepted that aspirin at low doses triggers lipotoxins production to block cell proliferation and chronic inflammation, which may associate with a lower incidence and recurrence of polyps as well as reduce colon cancer risk [2]
The standardized extraction of P. longifolia was through adding dried samples (leaves (Figure 1B), twigs, flowers, fruits, barks (Figure 1C) and/or roots) to adequate volume of methanol and soaked the samples for
Summary
According to the project of the world flora online webpage and Australia [9]. According to the project of the world flora webpage In Taiwan, it is commonly cultivated as landscape to avoid pollution [10]. Taiwan, it is commonly cultivated as landscape trees trees to avoid noisenoise pollution P. longfolia is a tall (up to 12 m) and evergreen tree that grows symmetrically and and produces green foliage The branches theare tree are peculiar, dropping produces green foliage The of theoftree peculiar, dropping down down toward ground, giving the plant a narrow slender shape. These features it toward ground, giving the plant a narrow slender shape These features make itmake readily readily available and is used in many folk medicines for the treatment of various ailments. Photos at Kaohsiung, Taiwan, 17 August, stem barkbark of P.of longifolia
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