Abstract
Phytochemical Screening of Solenostemon monostachyus and the Effect of Extract and Fractions on Castor Oil-Induced Diarrhoea in Rats
Highlights
Diarrhoea is a leading cause of malnutrition, and a second leading cause of death of children under five years globally.[1]
The phytochemical constituents in the leaves extract and fractions of S. monostachyus may be responsible for the observed in vivo antidiarrhoeal activity of the plant
The phytochemical screening of the ethanol extract revealed the presence of alkaloids, saponins, tannins, and cardiac glycosides
Summary
Diarrhoea is a leading cause of malnutrition, and a second leading cause of death of children under five years globally.[1]. Beauv (Lamiaceae) is among plants reportedly used in West and Central African ethnomedicine for the treatment and management of various health problems.[4] It occurs as an annual weed in anthropogenic habitats and rocky savannahs It is slightly succulent, aromatic, and has been reported to reach a height of 100 cm.[5] The aerial parts of the plant have so far been made into decoctions and utilised traditionally by the Ibibios of the South East Nigeria for the treatment of stomach ulcer, fever/malaria,haemorrhoid, and other inflammatory diseases.[6,7] The plant decoction has showed antihypertensive and antidiuretic potential.[8] The plant has been reported to possess antioxidant,[9,10] antihypertensive,[11] antimicrobial,[12] antiulcer,[13] antidiabetic and hypolipidemic,[14]. The study report, antidiarrhoeal potential of S. monostachyus to provide scientific basis for its use in ethnomedicine for diarrhoeal conditions
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