Abstract
Sesbania grandiflora is a medicinal plant that has been used by many Indonesian people. They have the ability as antibacterial because they contain bioactive compounds that inhibit bacterial growth. Sesbania grandiflora also contains other active compounds such as tannins, saponins, steroids, flavonoids, and terpenoids. This study aims to determine the antibacterial activity of extracts, n-hexane fraction, ethyl acetate fraction and water fraction of Sesbania grandiflora against Edwardsiella tarda using the well diffusion method in different concentration (75 ppm, 150 ppm dan 225 ppm), and knowing the active compounds of FTIR absorption bands. MIC ( minimum inhibitory concentration ) value of extract, n-hexane, ethyl acetate, and water fractions respectively was 0.51 %, 1.11 %, 0.97 %, dan 0.79 %. InIibitory zone diameter of the n-hexane fraction is most active against Edwardsiella tarda bacteria. The results of FTIR identification showed that n-hexane fraction contained flavonoids and terpenoids, as seen from absorption bands that function as antibacterial compounds. Keywords: antibacterial, Edwardsiella tarda, FTIR, Phytochemical Sesbania grandiflora .
Highlights
Increasing aquaculture production programs carried out during the period 2010-2014 has shown tangible results with an average increase of 23.8% per year
This study aimed to determine the antibacterial activity of extracts, n-hexane fraction, ethyl acetate fraction, and water fraction of Sesbania grandiflora against Edwardsiella tarda, and
The results showed that the concentration of n-hexane fraction was better in inhibiting the growth of E. tarda compared to ethanol extract, ethyl acetate fraction, and water fraction, with a large inhibition zone of 16.95 mm at a concentration of 225 ppm
Summary
Increasing aquaculture production programs carried out during the period 2010-2014 has shown tangible results with an average increase of 23.8% per year. In 2010 aquaculture production was 6.27 million tons. Whereas in 2014, it rose to reach 14.52 million tons. The value of temporary production in 2014 was Rp. 109.78 trillion [1,2]. Aquaculture development still faced with several global challenges and problems. One of the problems in aquaculture development is the development of fish and environmental health systems, where the disease is the main obstacle [3]
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