Phytochemical Screening and Test of Mucolytic Activity of Nira Stem Sente (Allocasia Macrorrhizos) by in Vitro

Abstract

Nira stem sente (Alocasia macrorrhizos) is one of the natural riches of Indonesia who have not much utilized, but since the age of the first communities in the Ciamis area using nira stem sente this as an alternative to relieve the symptoms of cough. As for the research on assay activity mucolytic nira stem sente (Alocasia macrorrhizos) there has never been, thus providing the inspiration for researchers to conduct research that aims to find out the chemical compounds and activity mucolytic from nira stem sente (Alocasia macrorrhizos). Nira stem sente (Alocasia macrorrhizos) accommodated overnight, then conducted screening phytochemical compounds, flavonoids, saponins, alkaloids, tannins, Quinones, triterpenoid. Next mucolytic activity testing nira stem sente (Alocasia Macrorrhizos) with variations in concentrations of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%. Artificial mucus using analog white duck egg. Raw comparison mucolytic using asetilsistein 0.1% and the negative control using 10 ml aquadest. Sample test consists of 10 ml of water from different concentration nira stem sente (Alocasia Macrorrhizos) in 100 ml of analog artificial mucus, then incubated at a temperature of 37°C for an hour and do a test mucolytic each interval of 15 minutes viskometer stormer. Testing conducted by as much as 3 times the replication.From the results obtained it was concluded that nira stem sente (Alocasia macrorrhizos) positive contain chemical compounds, alkaloids, flavonoids, saponins, tannins, Quinones, triterpenoid and all test groups have mucolytic activity. At all a concentration have mucolytic activity