Abstract
Objective: This study aimed to investigate the antioxidants and free radicals scavenging properties of ethanolic extracts from Tribulus terrestris fruit (TTF) and Mesua ferrea flower (MFF).Methods: The antioxidant and free radical scavenging activities were measured by using standard protocols against phytoextracts used at 50, 100, 150, 200 and 250 µg/ml concentration. Total phenolic and flavonoid content were estimated using Folin-Ciocalteu and aluminium-chloride reagent assay methods.Results: Among the extracts, MFF showed the highest total antioxidant ability followed by TTF. With regard to various scavenging activities, MFF had the highest radical scavenging activity than TTF extract closely resembled the standards. Also, the reducing capacity on ferrous ion was high in MFF than TTF. The quantified phenolic contents of TTF and MFF ethanolic extracts were 27.0±0.36 and 57.0±0.32 mg gallic acid equivalent per gram extract respectively. A positive correlation (p value<0.001) was observed between phenolic content and free radical scavenging efficiencies.Conclusion: The results confirm that both MFF and TTF are important sources of natural antioxidants and serves as an effective free radical scavengers and/or inhibitors. Hence, both extracts are suitable plant-based pharmaceutical products can be used to handle 'free radical-mediated diseases.
Highlights
Of late, plant-based pharmaceuticals have gained popularity and much interest has been focused on the discovery of new biologically active molecules by the industry and on the adoption of crude extracts of plants such as infusions, for selfmedication by the general public to handle free radical based adverse effects
From the results it was evident that both, terrestris fruit (TTF) and Mesua ferrea flower (MFF) extracts were found to be good source of polyphenols
MFF extract showed more amounts of phenolic and flavonoid contents compared to TTF extract
Summary
Plant-based pharmaceuticals have gained popularity and much interest has been focused on the discovery of new biologically active molecules by the industry and on the adoption of crude extracts of plants such as infusions, for selfmedication by the general public to handle free radical based adverse effects. Natural antioxidants, which are ubiquitous in fruits, leaves, and flowers, have received great attention and have been studied extensively [2], since they are effective free radical scavengers and are presumed to be less toxic than synthetic antioxidants. Considering the importance of natural product-based antioxidants in treating several human ailments, the present study was focused towards evaluation of antioxidant properties of Tribulus terrestris and Mesua ferrea plant extracts
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