Abstract
ObjectiveTo evaluate anthelmintic activity of methanolic extract of leaves of Terminalia citrina (T. citrina) plant belonging to the Combretaceae family. MethodsThe tests of phytochemical screening included alkaloids, flavonoids, tannins, saponins, quinines, anthocyanins, glycosides, carbohydrates and reducing sugars. The anthelmintic activity of methanolic extract of leaves of T. citrina was evaluated against Pheretima posthuma at three different concentrations (25 mg/mL, 50 mg/mL and 100 mg/mL) of extracts which involved determination of time of paralysis and time of death of worms. ResultsThe phytochemical screening of T. citrina leaves revealed the presence of flavonoids, tannins, alkaloids, carbohydrates and reducing sugars. The present study indicated that methanolic extract significantly exhibited paralysis and also caused death of worms especially at highest concentration of 100 mg/mL, as compared to standard reference Albendazole (10 mg/mL). ConclusionsThis study suggests that the leaves of T. citrina possess potent anthelmintic activity.
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