Abstract
Flavonoids are a group of polyphenolic compounds, which are widely distributed throughout the plant kingdom. Flavonoids of different classes exhibited various pharmacological and biological activities. The present study was undertaken to investigate the total flavonoids and antioxidant effect of Psoralea corylifolia seeds. The ethanol extract of Psoralea corylifolia seeds were prepared and performed its phytochemical screening. The total flavonoids and polyphenol were investigated to quantify the presence of polyphenol compounds. The 2, 2- diphenyl-1-picryl-hydrazil stable radical (DPPH) and Superoxide scavenging radical were used to determine extract antioxidant activity. The concentrations of flavonoids and polyphenol in ethanol extract of Psoralea corylifolia seeds were 60.63 QE. mg/gm and 74.35 GAE mg/gm respectively. The extract exhibited the strongest antioxidant activity with the lowest IC50 - value for DPPH and Superoxide scavenging. The IC50 value for DPPH and Superoxide scavenging were 166.61 μg/ml and 177.69 μg/ml respectively. The strongest antioxidant activity of ethanol extract could be due to the presence of flavonoids and phenols.
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