Abstract
Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Secondary constituents contain alkaloids, flavonoids, phenol, sapon in, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti-inflammation activities. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In Indian Ayurvedic system, Lagerstroemia Indica (Lythraceae) are well-known plants used for major and minor ailments. The aim of the present study is to examine leaf of Lagerstroemia Indica for phytochemical profile, antioxidant potential, antimicrobial including anti acne activity. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by FolinsCiocalteau reagent method and aluminium chloride method respectively. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The present study concluded that the crude extract of Lagerstroemia Indica is a rich source of secondary phytoconstituents which impart significant antioxidant potential. The extract of Lagerstroemia Indica possess antimicrobial effectiveness againt P. acne and other microbes, In Vitro anti acne activity. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries.
 Keywords: Lagerstroemia Indica, Phytochemical, Antioxidant, Antiacne.
Highlights
The aim of the present study is to examine leaf of Lagerstroemia Indica for phytochemical profile, antioxidant potential, antimicrobial including anti acne activity
This revealed that they contain various phytoconstituents which can be responsible for the anti acne activity
The anti-inflammatory activity of Lagerstroemia Indica ethanolic extract may be due to its ability to scavenge oxygen radicals which has been implicated in inflammation process
Summary
The word acne comes from the word acme meaning "the highest point", which comes from the Greek word akme meaning "point" or "spot". It was originally mispelt, with an 'n' rather than an 'm' in 1835. Medically known as Acne vulgaris, is a skin disease that involves the oil glands at the base of hair follicles. It commonly occurs during puberty when the sebaceous (oil) glands come to life and are stimulated by male hormones produced by the adrenal glands of both males and females. The defence mechanism of body acts to kill the bacteria, moulding in formation of whiteheads, blackheads, and pustules in these areas
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