Phytochemical profiling, and anti-oxidant, anti-bacterial, and anti-inflammatory properties of Viburnum coriaceum Blume

R V Anupama,M Haridas,Vijayakumar Vijaytha

doi:10.1186/s43094-020-00098-y

R V Anupama, M Haridas + Show 1 more

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https://doi.org/10.1186/s43094-020-00098-y

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Abstract

BackgroundViburnums comprise a taxonomic group of plants distributed all over the world and were reported to have many biological activities. Viburnum coriaceum Blume is one of the least explored members of the group. The present study was aimed to explore the phytochemical profile of the plant, Viburnum coriaceum Blume with special emphasis to its anti-oxidant, anti-bacterial, and anti-inflammatory activities.ResultsExtracts of all parts of plants were found to possess a spectrum of chemicals in considerable amount, including triterpenoids and glycosides. Anti-oxidant property was found in extracts made of any part of the plant. Methanol extract of root expressed a prominent zone of inhibition in agar gel well-diffusion assay involving many microorganisms. Inhibition of enzymes, LOX, and trypsin showed by the hexane extract of root suggested a prominent anti-inflammatory potential of the plant under investigation.ConclusionPhytochemical profiling and the other assays using the plant extracts provide us with a plant having many valuable medicinal properties. Viburnum coriaceum Blume could be noted as a promising material for drug leads.

Highlights

Viburnums comprise a taxonomic group of plants distributed all over the world and were reported to have many biological activities
Prepared hexane, methanol, and water extracts of the roots and aerial parts of V. coriaceum were used for qualitative analysis (Table 1)
As the anti-oxidant and anti-inflammatory potential of the plant extracts are appreciable, it can be considered for investigating anti-cancerous activities

Summary

Introduction

Viburnums comprise a taxonomic group of plants distributed all over the world and were reported to have many biological activities. The present study was aimed to explore the phytochemical profile of the plant, Viburnum coriaceum Blume with special emphasis to its anti-oxidant, anti-bacterial, and anti-inflammatory activities. Genus Viburnum is a group of around 200 shrubs and small trees, under the Adoxaceae family [1]. They are primarily distributed in the temperate climatic zone of Northern Hemisphere and in the tropical mountains of Australia and Tasmania. Great diversity among these plants are seen in the Himalayan regions and China [2]. They are found to be effective in muscle cramps, back pain, pain in thighs, etc. and animal/clinical studies

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