Phytochemical Investigation of the Roots of Jatropha Integerrima Jacq

Abstract

Jatropha integerrima Jacq. (Euphorbiaceae), is grown in many tropical and subtropical countries and used to treat eczema, herpes, ringworm, rheumatism, pruritus, scabies, toothaches, tumors and warts. Its latex is toxic. A methanolic extract of the roots was chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol successively in order of increasing polarity to isolate n-pentadecanyl oleate ( 1 ), α-D-glucopyranosyl-(2→1')-O-α-D-glucopyranoside (α-D-diglucoside, 2 ), n-hexanoyl-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranoside (n-caproyl O-α-D-pentaglucoside, 3 ), n-hexanoyl-O-β-D-glucopyranosyl-(2a→1b)-O-β-D-glucopyranosyl-(2b→1c)-O-β-D-glucopyranosyl-(2c→1d)-O-β-D-glucopyranosyl-(2d→1e)-O-β-D-glucopyranosyl-(2e→1f)-O-β-D-glucopyranoside (n-caproyl O-β-D-hexaglucoside, 4 ), α -D-glucopyranosyl-(2→1a)-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranoside (α-D-hexaglucoside 5 ) and α -D-glucopyranosyl-(2→1a)-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranosyl-(2e→1f)-O- α -D-glucopyranoside (α-D-heptaglucoside, 6 ) . The structures of these compounds have been established on the basis of spectral data analysis and chemical means.