Abstract
Extracts of aerial parts of Lotus corniculatus L. exhibited significant antioxidant, immunostimulant and anticancer activities [1]. Bioactivity-guided fractionation of the aerial parts of L. corniculatus led to the isolation of seven known compounds (1-7). The structure elucidation of the isolated compounds was achieved using spectroscopic techniques, including 1D and 2D NMR. Their chemical structures were identified as: 7,2'-dihydroxy-4'-methoxyisoflavan (vestitol) (1), kaempferol-3-O-rhamnoside (afzelin) (2), kaempferol-3,7-O-dirhamnoside (kaempferitin) (3), kaempferol-3-O-(2"-xylopyranosyl) galactopyranoside (4), soyasapogenol-β-3-O-glucopyranoside (5), soyasapogenol-β-3-O-[α-L-rhamnopyranosyl-(1'''→2'')-β-D-galactopyranosyl-(1''→2')-β-D-glucuronopyranoside] (soyasaponin I) (6) and methyl -O-β-D-glucopyranoside (7). Compounds 4 and 5 are reported for the first time from the genus Lotus.
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