Abstract
<i>Aloe gilbertii</i> belonging to the family Aloaceae is used by local people for treatment various disease such as malaria and wound healing. The main purpose of this study was to investigate phytochemicals and antioxidant activity of the Root Extract of <i>Aloe gilbertii Reynolds</i> Phytochemical screening of the CH<sub>2</sub>Cl<sub>2</sub>: CH<sub>3</sub>OH (1:1) extract revealed the presence of flavonoids, anthraquinone, Alkaloids, saponins, phenol and absence of steroids and phytosterols. The anti-oxidant potential and total antioxidant potential was determined by using reducing power determination method and phosphomolybdate method respectively. The antioxidant capacity of methanol, ethanol and ethyl acetate root extracts fractions of <i>Aloe gilbertii</i> were found to be 244.5±0.631, 241.5±0.112 and 106±1.05 mg of ascorbic acid per 10 mg of dry weight of antioxidant in the reducing power, respectively and it’s total antioxidant capacity of these extract fractions were 82.21±0.028, 88.75±0.016 and 74.85±0.043mg of ascorbic acid per 10 mg of dry weight of the crude extract. Thus, the results of the present investigation infer that this plant extracts possess potent antioxidant. Therefore it is strongly recommended to isolate the antioxidant components
Highlights
The rapid rise of degenerative diseases worldwide is threatening economic and social development as well as the lives and health of millions of people
This report agree with the previous report on root extracts of Aloe gilbertii [26]
The antioxidant capacity is measured on the basis of the ability to reduce ferric (III) ions to ferrous (II) ions
Summary
The rapid rise of degenerative diseases worldwide is threatening economic and social development as well as the lives and health of millions of people. Dietrelated high cholesterol, high blood pressure, obesity, and insufficient consumption of fruits and vegetables have been cited as significant interlinking risk factors that cause the majority of these diseases [2]. It is widely believed that at the epicenter of these diseases are highly reactive chemical species known as free radicals – electrically charged or neutral species having at least one unpaired electron. Cell damage caused by free radical-induced chain reaction appears to be a major contributor to aging and degenerative diseases such as cataracts, immune system decline, brain dysfunction, and many more [3]
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