Abstract
<p><strong>Objective: </strong>This study was conducted to identify the phytochemical constituents of <em>Leucaena leucocephala</em> leaf extracts using gas chromatography-mass spectrometry (GC-MS).</p><p><strong>Methods: </strong>Hexane, petroleum ether, chloroform, ethyl acetate and methanol leaves extract of <em>L. leucocephala</em> were analyzed using GC-MS, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standards and Technology (NIST) library.</p><p><strong>Results: </strong>GC-MS analysis of <em>L. leucocephala</em> leaves revealed the presence of 30 compounds and the major chemical constituents were Squalene (41.02%), Phytol (33.80%), 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (30.86%) and 3,7,11-Tridecatrienenitrile, 4,8,12-trimethyl (25.64%). Some of these compounds have been reported to possess various biological activities such as antioxidant, antimicrobial, hepatoprotective, antiparasitic, insecticide, nematicide, pesticide, anti coronary, antiarthritic, antiandrogenic, hypocholesterolemic, cancer preventive, anti-cancer, analgesic, anesthetic, allergenic and etc.</p><p><strong>Conclusion: </strong>The findings of this study indicating that<em> L.</em> <em>leucocephala</em> leaves possess various potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance.</p>
Highlights
Leucaena leucocephala trees or Petai belalang as it is locally known in Malaysia [1] is a tropical multipurpose tree species
To the best of our knowledge, since no information is available on the phytochemical screening of L. leucocephala leaves from Malaysia
This is the first study for the phytochemicals screening of L. leucocephala leaves from Malaysia
Summary
Leucaena leucocephala trees or Petai belalang as it is locally known in Malaysia [1] is a tropical multipurpose tree species. L. leucocephala was known as miracle tree because of its worldwide success as a long-lived and highly nutritious forage tree, used as firewood, timber, human food, green manure, shade and erosion control and it is estimated to cover 2-5 million ha worldwide [2, 3]. In Indonesia, Thailand, and Central America, people eat the young leaves, flowers, and young pods in soups [5, 6]. It is one of the medicinal plants used to control stomach ache, like contraception and abortifacient. Bioactivity studies on this plant revealed its anthelmintic, antibacterial, antiproliferative and antidiabetic activities [7]
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