Abstract
Phytochemical Composition and Antibacterial Activities of Syzygium polyanthum Methanolic Leaves Extract
Highlights
Antibacterial resistance is a serious clinical challenge worldwide because some of the bacteria develop enzymes that are capable of digesting and destroying antibiotic molecules
Phytochemical screening revealed the presence of alkaloids, saponin, terpenoids and steroid in methanolic leaves extract qualitatively and these compounds could be responsible for antibacterial properties of leaves extract of S. polyanthum
Results obtained in the present study revealed that the methanolic extract of S. polyanthum leaves exhibits antibacterial activity against S. aureus, methicillin-resistant Staphylococcus aureus (MRSA), S. pyogenes and K. pneumoniae but not E. coli
Summary
Antibacterial resistance is a serious clinical challenge worldwide because some of the bacteria develop enzymes that are capable of digesting and destroying antibiotic molecules. The highest antibacterial activity against bacteria S. aureus and E. coli is shown using the n-hexane extracts.[6] This can be explained by the active compounds in the nonpolar fractions in relatively higher concentration which is responsible for the antibacterial activity of the extract Both extracts were observed to inhibit Gram positive and Gram negative bacteria tested in vitro to suggest that S. polyanthum leaves extract and fractions has a broad-spectrum antibacterial activity. Objectives: This present study was conducted to evaluate phytochemical compounds and antibacterial activities of methanolic extract of S. polyanthum leaves. The extract was found to exert antibacterial activity against four tested bacteria which are S. aureus, S. pyogenes, MRSA and K. pneumoniae except for E. coli. Phytochemical screening revealed the presence of alkaloids, saponin, terpenoids and steroid in methanolic leaves extract qualitatively and these compounds could be responsible for antibacterial properties of leaves extract of S. polyanthum.
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