Abstract
Diabetes is a metabolic disorder by a chronic hyperglycemic condition because of defects in insulin secretion and insulin action or both. Minor cereals are often drought tolerant and fertilizer efficient. In this review we focus the content and bioavailability of phytochemicals in some minor cereals on the basis evidence for increasing plasma phytochemical concentrations and reducing oxidative stress as well as inflammation in humans. Phenolics and Flavanoids are major phytochemicals and may be available with high concentration in minor cereals but as tightly attached with cell wall, their bioavailability is mostly limited. Clinical trials concluded that vitamin E and other common antioxidants were not helpful for managing diabetic complications. Vicious cycles can cause type 1 DM, where as hypoglycemia can forward to down and regulate neuroendocrine. Increased phytochemical bioavailability may be achieved through bio processing of grains but the improvements might be small and have not yet led to changes in clinical associated with reduced risk of T2D. Furthermore, the effects of minor cereals against oxidative stress in healthy individuals can be very low or not occurred but systemic inflammation can be reduced in people after huge intake. More than 300 Indian medicinal plants have antidiabetic property but exact mechanisms for hypoglycemic action of many plants are still unknown. Further studies are required to pay attention toward direct role of minor cereal phytochemicals on alarming diseases diabetes.
Highlights
Diabetes mellitus (DM) and type 2 diabetes (T2D) both are current health problems which affect millions of individuals worldwide and increase dangerously, but among the total population of diabetic patients more than 90% suffer from Type 2 Diabetes (T2D)
In this review we focus the content and bioavailability of phytochemicals in some minor cereals on the basis evidence for increasing plasma phytochemical concentrations and reducing oxidative stress as well as inflammation in humans
The cause of Diabetes mellitus (DM) is metabolic disorder of multiple physiology by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism defects in insulin secretion and insulin action, or both
Summary
Diabetes mellitus (DM) and type 2 diabetes (T2D) both are current health problems which affect millions of individuals worldwide and increase dangerously, but among the total population of diabetic patients more than 90% suffer from Type 2 Diabetes (T2D). Minor cereals intake can reduce the risk of T2D [9] [10] [11]. Various studies demonstrated that frequent intake of minor cereal foods improves metabolic homeostasis and delays or prevents the development of T2D and its complications in a variety of associates, but in mostly of European pedigree [12]-[18]. There are many different experimental studies provide evidences between minor cereal intake and diabetes prevention [15] [18]. Minor cereal foods can improve the index of diabetes risk, including glycemic control, fasting plasma insulin, glucose, and insulin sensitivity, as well as include in the management of those individuals with or at high risk of developing T2D [13] [19] [20] [21]. Cereal fiber can play important role to reduce the diabetes risk associated with minor cereal consumption [24]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
