Phytochemical and chemotaxonomic study on Atractylodes lancea

Abstract

Based on previous studies on Atractylodes lancea (Thunb.) DC., this paper focuses on the chemical composition of fresh rhizome of Atractylodes lancea. And fifteen compounds were isolated, including six guaiane-type sesquiterpenoids (1–5), one eudesmane-type sesquiterpenoid (6), one monoterpene glycoside (7), one polyacetylene glycoside (8), one phenylpropanoid glycoside (9), two nucleosides (10–11), one alkaloid (12), one amino acid (13), one purine (14) and one fatty acid (15). The structures of the isolated compounds (1–15) were elucidated by 1H and 13C NMR spectroscopic analyses and comparisons with previously reported data. Compounds 7 and 12 were isolated from the Compositae family for the first time. Compound 11 was isolated from genus Atractylodes for the first time. Compound 14 was isolated from this plant for the first time. Furthermore, the chemotaxonomic significance of these isolates was discussed.