Abstract

The phytochemistry ofAchornea cordifolialeaf extract using different solvents was studied using standard methods. The effects of the leaf extract on some pathogenic bacteria and fungi were also examined. The Phytochemical screening of the leaves shows the presence of useful ethno-botanical bioactive substances such as tannin, saponin, flavonoid, cardiac glycoside and anthraquinone, while alkaloid, phlobatanin and terpene also tested for were absent. The butanol fraction of the extract gives the highest zone of inhibition (13.0 mm) againstStaphylococcus aureus, Escherichia coliandpseudomonas aeruginosa, which are in parity. The control, gentamycin injection gives 12.5 mm, 11.0 mm and 12.0 mm respective zones of inhibition against theStaphylococcus aureus, Eschariclia coliandPseudomonas aeruginosa. Also, the butanol fraction of the extract shows highest zone of inhibition of 17.0 mm againstCandida albican, while ethanolic extract gives 13.0 mm zone of inhibition againstTrichophyton violaceum.

Highlights

  • The Nigerian Vegetations are rich in Medical Plants These plants are usually employed in traditional medicines as remedies for treatment of various ailments

  • The result shows that Candida albican exhibits the highest zone of inhibition of 17.0 mm with butanol fraction of the extract

  • Escherichia coli, Pseudomonas aeruginosa, Satphylococcus aureus and Candida albican were all resistant to n-hexane and chloroform fractions but sensitive to ethyl acetate fraction

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Summary

Introduction

The Nigerian Vegetations are rich in Medical Plants These plants are usually employed in traditional medicines as remedies for treatment of various ailments. Addition of 0.5 g of leaf extract with Fehlings solution A and B and boiled resulted in the formation of precipitate which was taken as positive test for the presence of saponin. The microorganisms were Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albican and Trichophyton violaceum.

Results
Conclusion
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