Abstract

The objective of present research work was to determine the antioxidant activity and presence of secondary metabolites in bark of Pterospermum acerifolium belonging to family Sterculiaceae. The phytochemical analysis of bark of Pterospermum acerifolium showed the presence of anthraquinones, cardiac glycosides, flavonoids, saponins and tannins while alkaloids were absent. Oxidative compounds are responsible for prognosis of many diseases like Alzheimers disease, ischemic heart disease, Parkinson disease and atherosclerosis. Antioxidants are the compounds responsible for curing such ailments that are produced by oxidative stress to the cells. Antioxidant activity of bark of Pterospermum acerifolium was determined by 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH). Extracts of plant material were prepared in dichloromethane and methanol solvents. Gallic acid was used as standard drug. Methanol extract exhibited excellent radical scavenging activity with IC 50 14.506 0.07.

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