Abstract

Plants have been recognized long ago as rich sources of natural products for the treatment of a wide spectrum of diseases. It has been reported that plant extracts are commonly used in traditional medicine and its contribution with respect to health coverage was estimated for over 80% of the world’s population, especially in the developing world. The present investigation, qualitatively evaluated the present of some certain phytochemicals in the crude extract of the macerated plant stem obtained from three solvents (ethanol 90%, distilled water and chloroform). Ethanolic extract shows higher presence of phytochemicals over water and chloroform extract. The in-vitro antibacterial activity of crude extract of the plant’s stem was tested on one gram positive bacteria (Staphylococcus aureus) and one gram negative bacteria (Escherichia coli). The test was performed by simple Agar diffusion Assay. Zone of inhibition (mm) of the extracts was determined. Of the various extract that was tested ethanolic extract was the one which shows remarkable effect on the microbes (Escherichia Coli 9.40mm and Staphylococcus Aureus 14.60mm). Based on these discovery it might be concluded that Calligonum polygonoides possessed great potential against these human pathogens. It might also be speculated that these plant extract can be subjected to further chemical and biochemical analysis to characterize their chemical constituents and the chemical compound responsible for the antibacterial activity.

Highlights

  • Plants have been recognized long ago as rich sources of natural products for the treatment of a wide spectrum of diseases

  • It has been reported that plant extracts are commonly used in traditional medicine and its contribution with respect to health coverage was estimated for over 80% of the world’s population, especially in the developing world [1]

  • The phytochemical screening of stem extracts indicate the presence of very important phytochemicals, with the ethanolic extract having to show higher presence of phytochemicals, over water extract and chloroform

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Summary

Introduction

Plants have been recognized long ago as rich sources of natural products for the treatment of a wide spectrum of diseases. Because of the numerous side effects of these drugs, the value of medicinal plants is being rediscovered as some of them have proved to be as effective as synthetic medicines with fewer or no side effects and contraindications. It has been proved that the effects of natural remedies may seem slower, the results are sometimes better on the long run especially in chronic diseases [2]. Calligonum Polygonoides Linn belongs to the family Polygonaceae, locally known as phog, phogala or phogaro [3]. It is an endangered plant specie, with both food and medicinal value. Polygonoides can be used as; the aqueous paste of plant acts as an antidote against the

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