Abstract
1. The mechanism that initiates adult development after pupal diapause has been studied in a total of 282 experiments, supplementary to those reported previously.2. Brainless, diapausing pupae were divided transversely and the developmental capacities of anterior and posterior fragments tested and compared.3. Implantation of a previously chilled brain sufficed to terminate the dormancy of anterior fragments.4. Isolated abdomens, to the contrary, remained undeveloped after brain implantation. Yet such abdomens, even without implantation, could be induced to develop by grafting them to developing anterior fragments. Manifestly, the abdomens required for development an additional factor normally produced in the anterior end of the pupa.5. By transections at various levels the source of this additional factor was found to be the thorax.6. A testing of various thoracic organs revealed the effectiveness of the glands. Thus, implantation of a chilled brain plus prothoracic glands induced the comple...
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