Abstract
Physiology and Plasticity of Interhemispheric Connections
Highlights
What precisely is the function of the CC? What are the cellular and molecular mechanisms that persuade a set of cortical axons to take a route to the contralateral hemisphere? Which signals are responsible for the topography of callosal connections? Is the CC modifiable in the adult brain? These questions are addressed in many recent studies and are represented by the papers collected in this issue
Polonara provide a functional map of callosal topography by charting the BOLD signal evoked in callosal axons by taste, tactile, auditory, and visual stimuli and by motor tasks
In the visual cortex, CC connections have a multiplicative shift of the responses and this is an interesting finding that goes beyond the old debate of whether callosal connections are excitatory or inhibitory
Summary
What are the cellular and molecular mechanisms that persuade a set of cortical axons to take a route to the contralateral hemisphere? Which signals are responsible for the topography of callosal connections? Polonara provide a functional map of callosal topography by charting the BOLD signal evoked in callosal axons by taste, tactile, auditory, and visual stimuli and by motor tasks.
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