Abstract

This review deals with the neuro-hormonal changes in congestive heart failure, a syndrome that is usually initiated by a reduction of cardiac output. In order to do this, we should like to 1) summarise previous and more recent evidence for a number of these neuro-hormonal derangement’s, 2) review the experimental evidence for an abnormality in the function of the arterial- and cardiopulmonary baroreceptor reflexes and 3) discuss, whether this abnormality or an interaction with renal mechanisms might cause the neuro-hormonal derangements in congestive heart failure.

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