Abstract
Hypertension is common in continuous flow LVAD (CFLVAD) patients and is linked to major adverse events like stroke and aortic incompetence. The human circulation was modelled with wave propagation and reflections using physiologic data from ADAN 86, with a set of 86 arteries including the cerebral vessels. 1. Blood pressure was compared for a flow of 5 litres/minute for a normal pulsatile flow and CF LVAD with varying degrees of pulsatility RESULTS: CONCLUSION: Restoring physiologically significant pulsatility is likely to restore normal blood pressure with significant reduction in adverse events like stroke, aortic incompetence and gastric bleeds. The degree of pulsatility needed to achieve this needs further study.
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