Physiological Changes of Thyroid Hormones in Women with Osteoporosis in Iraq / Basra Province

Mustafa A Almajeed,Sami J Kathim

doi:10.30526/2021.ihicpas.2650

Abstract

Osteoporosis is described as sickness due to fading bone mass and microarchitecture spoilage of bone tissue leads to consolidation bone fragility and increase risk of fracture. The relationship between osteoporosis and thyroid is important by of the skeleton bones in turnout of circulating physical thyroid hormone and TSH condensation to reduced bone mineral loss in osteoporosis patients, also researcher derives that hormone thyroid and TSH scale increased bone resorption, by increase bone mineral deposition. (110) patients female transfer from provincial and civilian habitation, their ages between (55-75) years old, they pay a visit to DEXA station to measure the density. The samples of blood after diagnosis of disease were taken, then the thyroid hormones were gauged by the modern VIDAS automated quantitative device according to the methods which assay serum or plasma. The outcome appeared to decrease significantly (pâ‰¤0.05) in TSH, T3, and T4 in osteoporosis women compared with healthy women, also no significant changes occur between housing status. Thyroid hormones have significant changes in osteoporosis women matched with good health women in Iraq / Basra province.

Highlights

Osteoporosis is an important disease associated with increased mortality after fractures [1]
The percent of high fractures risk in people have decreased in bone mineral density, the fractures majority will be found in patients with decrease density of bone rather than osteoporosis because the individuals with bone mass in this range are a high number [3]
Measurement of Thyroid Hormone For the determination of thyroid hormone (TSH, T3, T4) the modern VIDAS automated quantitative device, these trials were examined in a specialist laboratory according to the methods which assay by using the Enzyme-Linked Fluorescent Assay (ELFA) technique to plasma or serum [9]. 2.5

Summary

Introduction

Osteoporosis is an important disease associated with increased mortality after fractures [1]. The age between (55-75) years old and weighing between (50-70 kg) while the length of this patient about (145-165 cm) Those patients visited al Zahraa clinic in Ibnalbetar private hospital to quantum the density of bone mineral by measure the hips and lumbar spine density using Lunar Prodigy (version 16) a dual-energy x-ray absorptiometry (DEXA) from (USA). Dual Energy X-ray Absorptiometry The technique of choice to diagnose osteoporosis and to monitor the response to treatment is called (DXA, DEXA) Dual-energy X-ray absorptiometry Figure (1). It is considered a useful for body composition measuring. The (WHO) known as World Health Organization has assign criteria for assessing the risk of fracture after diagnosis of osteoporosis by employ DXA screening, bone mineral density value at the hip or spine that is above 2.5 SDs under the optimal average health young people of the same perspiration and genus clarifies individuals have osteoporosis (T- score ≤ -2.5) [8]

Sample Collection

Results

Discussion

Conclusion