Abstract

Research on the natural resources found in medicinal plants and endophytes makes important contributions to a wide variety of fields, including drug development, agribusiness, biotechnology, and sustainable development. Endophytes are a group of microorganisms that can be discovered in the rhizosphere of plants being used in medical treatment. These microorganisms have the capability of producing a wide range of primary and secondary metabolites by utilizing a variety of distinct biosynthetic pathways. Several different technologies, such as genetic modification and artificial intelligence (AI), play a significant role in the acceleration of endophytic research. These methods aid in the discovery and synthesis of novel compounds with medicinal promise, the predictive analysis of bioactive compounds, the identification and classification of endophytes, and the optimization of potential bioactive compounds. In light of this, the current review focuses on providing a concise comprehension of the influence of bioactive compounds secreted by specific endophytes on medicinal plants through the application of significant technologies in the field of endophytic research.

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