Abstract
While proton imaging has become a routine diagnostic modality, sodium imaging has been difficult to obtain because of its inherent weakness in signal strength due to significantly lower concentration in tissue. -This difficulty of poor signal to noise ratio can be over-come in several ways, by using 3 dimensional data acquisition rather than 2 dimensional, a better low-noise electronics and fast pulse repetition rate for more signal averaging and multi-echo acquisition. The biochemical properties of sodium, yielding a dramatic contrast changes associated with pathology, also lead to facilitate favorable conditions for clinical imaging compared with proton imaging. The combined use of the advanced imaging techniques and the biochemical properties of sodium can produce clinically useful images. We have demonstrated an additional use of sodium imaging by obtaining simultaneous images of proton and sodium for direct comparison of the two distinctly different but related modalities.
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